TNFAIP6 antibody

Catalog No. ABIN7120409

The Rabbit Polyclonal anti-TNFAIP6 antibody has been validated for WB, ELISA and IHC. It is suitable to detect TNFAIP6 in samples from Human, Mouse and Rat.

Quick Overview for TNFAIP6 antibody (ABIN7120409)

Target: TNFAIP6 (Tumor Necrosis Factor-Inducible Protein 6 (TNFAIP6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNFAIP6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-TNFAIP6 Antibody

Purpose: TNFAIP6 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: tumor necrosis factor, alpha-induced protein 6

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for TNFAIP6

Target: TNFAIP6 (Tumor Necrosis Factor-Inducible Protein 6 (TNFAIP6))

Alternative Name: TNFAIP6

Background:

Synonyms: Tumor necrosis factor-inducible gene 6 protein|Hyaluronate-binding protein|TNF-stimulated gene 6 protein (TSG-6)|Tumor necrosis factor alpha-induced protein 6 (TNF alpha-induced protein 6)|TNFAIP6|TSG6

Background: The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis.

Molecular Weight: 41 kDa

Gene ID: 7130

UniProt: P98066